Trail Blazers vs. Nuggets odds, line, spread: 2021 NBA picks, Nov. 23 predictions from model on 115-76 roll

The Portland Trail Blazers and the Denver Nuggets take the court for a matchup on Tuesday in the national spotlight. Both teams are aiming to contend in the Western Conference with winning records in 2021-22. Portland is 9-8 overall and an impressive 8-1 at home. Denver is also 9-8 but just 2-5 away from home this season. Nikola Jokic (wrist) is listed as questionable for Denver, with Michael Porter Jr. (back) and Jamal Murray (knee) ruled out. Portland's injury report is clean for Tuesday's game.

Tipoff is at 10 p.m. ET in Portland. Caesars Sportsbook lists Portland as a 5.5-point favorite at home, while the over-under, or total number of points Vegas thinks will be scored, is 212.5 in the latest Nuggets vs. Blazers odds. Before locking in any Nuggets vs. Trail Blazers picks, be sure to see the NBA predictions and betting advice from SportsLine's proven model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 6 of the 2021-22 NBA season up over $1,200 on all top-rated NBA picks this season. It's also on a stunning 115-76 roll on top-rated NBA picks against the spread that dates back to last season. Anyone following it has seen huge returns.