World Cup 2022 Uruguay vs. Ghana start time, betting odds, lines: Top model picks, FIFA predictions, best bets

Ghana and Uruguay will both be playing for a berth in the knockout stage when they meet in a Group H matchup on Friday in the 2022 World Cup. While certain tiebreaker scenarios would allow either team to advance with a draw, a win would send the victor through to the next round alongside Portugal. Ghana lost 3-2 to Portugal last Thursday, then prevailed over South Korea by the same score on Monday. On those same dates, Uruguay played a scoreless draw with South Korea and lost 2-0 to Portugal. Ghana will advance with a win, and can also do so with a draw unless South Korea manages to defeat Portugal. Uruguay are through with a win, but if South Korea also prevails, Portugal's companion in the knockout stage would be determined by tiebreakers.

The match from Al Janoub Stadium in Al-Wakrah, Qatar, will kick off at 10 a.m. ET. Caesars Sportsbook lists Uruguay as the -150 favorites (risk $150 to win $100) on the money line in the latest Ghana vs. Uruguay odds. Ghana are the +400 underdogs, a draw is priced at +280 and the over/under for total goals is set at 2.5. Before locking in any Uruguay vs. Ghana picks, you need to see the World Cup predictions and betting advice from SportsLine's proven soccer simulation model.

The SportsLine soccer simulation model evaluates a team's offensive and defensive capabilities based on the game situation. Then, it assigns a grade using an expected payout-to-probability ratio. The model was accurate on 56% of all picks during the Champions League group stage and returned more than $1,000 to $100 bettors on its A+ picks. It also went 17-9-2 (+526) on spread picks to start the World Cup. Anyone who has followed it has seen huge returns.